The increasing demands for more accurate flow measurements have made the study of pulsating flow effects crucial for the further development of flowmeters. This paper presents the development of an experimental test facility with an integrated water-flow pulsator for experimental investigations of the water pulsation effects on flowmeters. The mechanical implementation of the measurement system with a built-in pulsator was developed with the help of mathematical modeling of the entire test system using the method of characteristics. The developed flow pulsator is able to generate reproducible water flow pulsations with defined properties, such as the frequency and amplitude of the pulsating flow. The water-flow pulsator's characteristics were experimentally confirmed by a spectral analysis of the generated water flow pulsations, which were measured with an orifice plate flowmeter. The orifice plate flowmeter was calibrated in pulsating flow conditions, where a temporal inertia constant was introduced to minimize the temporal inertia effects of water on the instantaneous pulsating flow measurement accuracy. The orifice's temporal inertia constant was derived mathematically from the results of the pulsating flow measurements considering linear theory assumptions.